Job Description

AbbVie is a global, research-based biopharmaceutical company committed to developing innovative therapies for serious health conditions. In our growing Genetic Medicine group at Abbvie South San Fransisco, we are seeking a Principal Research Scientist to lead to apply cutting-edge technologies to deliver innovative new therapies. The ideal candidate will have a strong background in molecular and cellular biology, a track record of successful project leadership, and a passion for advancing genetic medicine. As one of the key team members, this individual will work with the manager and scientists across different functional groups to discover and develop next generation non-viral genetic medicine. 

Key Responsibilities:

Lead the design and development of fusion proteins for therapeutic purposes suitable for mRNA delivery by nanoparticles.

Characterize expressed protein by biochemical or flow-based techniques and evaluate function by plate-based or cell-based assays.

Closely collaborate with antibody discovery/production team to bridge between Biotherapeutics and Genetic Medicine.

Co-lead project with Therapeutic Area to identify and optimize therapeutic candidates and take accountability for project deliverables.  

Analyze experimental data, interpret results, and present findings to internal and external stakeholders. Prepare publication-quality reports and contribute to scientific manuscripts and patents as a lead scientist.

Mentor research associates on experimental design, troubleshooting, assay optimization and data interpretation. Foster a collaborative and innovative research environment.