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Postdoctoral Research Associate Position in Mucosal Immunology

Posted on Jan 16, 2019 by Washington University School of Medicine in Saint Louis

Saint Louis, MO 63110
Research & Development
Immediate Start
Hourly Salary

Job Description

Postdoctoral Research Associate Position in Mucosal Immunology

Desired area of expertise mucosal immunology

The Newberry laboratory in the Department of Medicine at Washington University School of Medicine in Saint Louis Missouri, USA is seeking to hire a postdoctoral fellow. This postdoctoral position will lead basic discovery research studies in the intestinal immune system. Techniques used in these studies include in vivo two photon imaging, multi-parameter flow cytometry and flow cytometric cell sorting, single cell RNA sequencing, ex vivo cellular assays, and multiple animal models. This is a unique opportunity to be trained in a wide array of techniques in a growing area of mucosal immunology, which can serve as a platform for a career as an independent investigator or a lead investigator in industry.

Publications related to the project:

1. J. R. McDole et al., Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine. Nature 483, 345-349 (2012).

2. K. A. Knoop, K. G. McDonald, S. McCrate, J. R. McDole, R. D. Newberry, Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon. Mucosal Immunology 8, 198-210 (2015).

3. K. A. Knoop, K. G. McDonald, D. H. Kulkarni, R. D. Newberry, Antibiotics promote inflammation through the translocation of native commensal colonic bacteria. Gut 65, 1100-U1160 (2016).

4. K. A. Knoop et al., Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria. Sci Immunol 2, (2017).

5. D. H. Kulkarni et al., Goblet cell associated antigen passages are inhibited during Salmonella typhimurium infection to prevent pathogen dissemination and limit responses to dietary antigens. Mucosal Immunol, (2018).


Trains under the supervision of a faculty mentor including (but not limited to):

1. Manages their own project, which should lead to a first author publication.
2. Develops expertise in cellular immunology techniques, imaging techniques, animal models.
3. Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature.
4. Presents scientific work both inside and outside the University with excellent oral communication skills.
5. Assists with grant preparation and reporting.
6. Prepares and submits papers on research with excellent writing skills.
7. Designs research experiments.
8. Evaluates research findings and reports results.
9. Conscientious discharge of his/her research responsibilities.
10. Maintain conformity with ethical standards in research.
11. Maintain compliance with good laboratory practice including the maintenance of adequate research records.
12. Engage in open and timely discussion with his/her mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
13. Collegial conduct towards co-trainees, staff members and members of the research group.
14. Adherence to all applicable University policies, procedures and regulations. All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University.

Job Type/Schedule:
This is a fulltime position

Compensation and Benefits:
Compensation and Benefits follow the guidelines set by the Division of Biology and Biomedical Sciences at Washington University School of Medicine in Saint Louis, MO. Please see for details. Current starting salary for postdoctoral fellows at Washington University School of Medicine in Saint Louis for fiscal year 2019 (July 1, 2018-June 30, 2019) is $47,484 not including fringe benefits.

Job Requirements

Desired qualifications:
PhD or MD, PhD degree.
Fluent in the English language with writing skills.
Previous work in immunology preferred, but not required.

How to apply:
Please email curriculum vitae or biosketch, research statement, and the names and email addresses of three references to:

Information about Washington University School of Medicine:
Washington University School of Medicine was founded in 1891 and has over 1,200 students, 600 of which are pursuing a medical degree with or without a combined Doctor of Philosophy or other advanced degree. It also offers doctorate degrees in biomedical research through the Division of Biology and Biological Sciences. There are over 1,000 faculty, 1,000 residents, and 700 fellows. Washington University School of Medicine consistently ranks in the top ten medical schools overall and in research. Washington University Medical Center comprises 164 acres (0.5 km²) spread over approximately 17 city blocks, located along the eastern edge of Forest Park within the desirable Central West End neighborhood. The Medical Complex is accessible via the Central West End MetroLink station, which provides transportation to the rest of Washington University's campuses. For additional details about Washington University School of Medicine see:

Reference: 615418386

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