This Job Vacancy has Expired!

Postdoctoral Fellow in RNA Biology

Posted on Jul 10, 2022 by Thomas Jefferson University

Philadelphia, PA 19107
Research
Immediate Start
Hourly Salary
Full-Time
Job Description
Multiple postdoctoral researcher positions are available for NIH-funded research in the lab of Dr. Yohei Kirino at Computational Medicine Center (CMC)/Department of Biochemistry and Molecular Biology in Thomas Jefferson University (TJU). Overall research goal of the Kirino lab is to understand the biogenesis mechanism and molecular function of short non-coding RNAs (ncRNAs) and use the knowledge for development of novel biomarkers and therapeutic applications in diseases. By taking advantage of RNA biology/biochemistry, molecular/cellular biology, and computational biology, the Kirino lab is particularly focused on transfer RNA (tRNA)-derived ncRNAs, cyclic phosphate-containing RNAs (cP-RNAs), and Piwi-interacting RNAs (piRNAs), which play crucial roles in various biological processes and diseases (). Job Requirements
Highly-motivated individuals with strong background in RNA biology and/or molecular/cell biology are awaited. Experience on bioinformatics analysis or animal research is advantageous but not essential. Applicants should have a Ph.D. degree, a productive track record, and a high writing and communication skills. The successful applicant will have a unique opportunity to work in close collaboration within CMC, the Department, and with other research groups in TJU, UPENN, and other institutions.

Applicants should send 1) a cover letter with a description of past research experience and future research/career goals, 2) CV, and 3) contact information of 3 references to Dr. Yohei Kirino at .

Contact information:

Yohei Kirino, Ph.D.
Computational Medicine Center
Department of Biochemistry and Molecular Biology
Sidney Kimmel Medical College
Thomas Jefferson University
1020 Locust Street, Jefferson Alumni Hall 222
Philadelphia, PA 19107
Email:

Selected recent publications:

Shigematsu, M., et al. RNase K promotes robust piRNA production by generating 2 ,3 -cyclic phosphate-containing precursors. Nature Communications, 12 (1): 4498, 2021. Pubmed

Pawar, K., et al. Infection-induced 5 -half molecules of tRNAHisGUG activate Toll-like receptor 7. PLoS Biology, 18 (12): e, 2020. Pubmed

Shigematsu, M., et al. Genome-wide identification of short 2 ,3 -cyclic phosphate-containing RNAs and their regulation in aging. PLoS Genetics, 15 (11): e, 2019. Pubmed

Honda, S., et al. The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. Nucleic Acids Research, 45: 9, 2017. Pubmed

Shigematsu, M., et al. YAMAT-seq: an efficient method for high-throughput sequencing of mature tRNAs. Nucleic Acids Research, 45: e70, 2017. Pubmed

Honda, S., et al. Selective amplification and sequencing of cyclic phosphate-containing RNAs by the cP-RNA-seq method. Nature Protocols, 11: 476-489, 2016. Pubmed

Honda, S., et al. Sex hormone-dependent tRNA halves enhance cell proliferation in breast and prostate cancers. Proceedings of the National Academy of Sciences, USA, 112: E3816-E3825, 2015. (Featured in In This Issue) Pubmed Please don't forget to mention Bio Careers when applying for the job.

Reference: 1663875769

Set up alerts to get notified of new vacancies.

Similar Jobs

Postdoctoral Fellow in RNA Biology

Philadelphia, PA

Hourly Salary