Senior Research Associate/ Associate Scientist

Posted on Nov 16, 2018 by Iovance Biotherapeutics, Inc.

Tampa, FL 33601
Research & Development
30 Oct 2018
Annual Salary
The Senior Research Associate/Associate Scientist will work on developing methods to optimize the anti-tumor activity of tumor infiltrating lymphocytes (TILs) for therapeutic applications. Such methods may include ex vivo manipulation of T cell co-stimulatory and co-inhibitory pathways, T cell subsets selection strategies, identifying neoepitopes derived from the tumor mutanome, as well as developing genetically-engineered TILs with enhanced in vivo persistence and therapeutic activity.

Specific Responsibilities

Perform research experiments involving a variety of protocols and technics. Reliably implement, troubleshoot, and read out state-of-the-art cellular biology techniques.
Analyze and interpret experimental results. Make detailed observations and record them in a timely and relevant fashion.
Organize results for team presentation and discussion.
Investigate and develop new methods and technologies necessary to project advancement.
Maintain high level of professional expertise through regular consulting of scientific literature and attendance of training and/or scientific seminars.
Contribute to scientific publications.
Help identifying patentable inventions.

Education and Qualifications

Master's degree in Cellular Biology, Molecular Biology, Immunology, or related discipline required.
5-8 years of post-degree bench research experience, preferably in industry, required.
Immunology and/or oncology background. Knowledge about immune response mechanisms and their modulation during cancer development a plus.
Extensive tissue culture experience using primary and established cell lines, familiarity with in vitro T cell functional assays as well as flow cytometry staining and acquisition techniques expected.
Experience with gene cloning and other molecular biology techniques (qRT-PCR, transfection) helpful.
Ability to independently carry out all lab experiments.
Highly motivated individual, quick learner, adaptable as new situations arise, and definite team player with a positive attitude.
Excellent record keeping and organization skills.
Effective communicator (verbal and written).

Reference: 560903481

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