Role of sterol metabolism in host response to virus
Posted on Dec 2, 2020 by National Institute of Environmental Health Science
Durham, NC 27709
A postdoctoral fellow with expertise in virology is sought for studies of the role of cellular
cholesterol metabolism in the host response to virus. The primary focus will be on
Coronaviridae and will include therapeutic strategies potentially applicable to SARS-CoV-2
that are under active study in the laboratory. Studies will utilize epithelial cell culture
(primary and cell lines) and may also employ organoids and mouse models.
This position is in the Host Defense Group of the Immunity, Inflammation and Disease
Laboratory (IIDL), a Branch within the intramural research program of the NIEHS, located
in Research Triangle Park, NC. The NIEHS has extensive core facilities, including cores in
bioinformatics, genomics, bioinformatics, flow cytometry, proteomics, metabolomics,
imaging, viral vectors, protein expression, and transgenic mouse production that together
offer the trainee wide latitude in the design and pursuit of their research questions.
Fellows are well-supported by stable funding and have access to extensive, free training
and career development opportunities.
Applicants must be very close to obtaining, or have a Ph.D. and/or M.D., ideally with less
than 5 years of postdoctoral training. Expertise in sterol metabolism is not essential,
whereas a solid background in virus-centered assays and related cell/molecular biology is
Please do not forget to mention Bio Careers when applying.