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Principal Scientist - Antibody Rational Design

Posted on Feb 11, 2020 by Michael Bailey Associates - Munich

Lausanne, Vaud, Switzerland
1 Apr 2020
Annual Salary

We are working with an exciting new client on a huge opportunity for Scientists of all levels to participate in the research and development of next generation of multispecific antibodies for Immuno-Oncology, inflammatory diseases and autoimmune diseases.

We are looking for a Principal Scientist who will lead antibody discovery projects from inception to industrialisation.


  • Lead discovery projects right from inception to industrialisation of multispecific antibodies.
  • Participate in the development of innovative solutions to engineer and characterize antibodies and novel antibody formats
  • Lead Fc engineering projects
  • Support team to address complex processes and transition leads for industrialization
  • Adhere to timelines and work cross functionally across different Matrix teams located within and outside of Switzerland.
  • Support communications, presentations, publications in journals as well as collaborations with academia and other companies.
  • Coach and mentor scientists, PhD students, interns and technicians.


  • Ph.D. in Molecular Biology, Biochemistry, Structural Biology or related fields with at least 5 years of relevant industrial experience. MSc with 8 years of relevant industrial experience will be considered.
  • Hands-on experience with making T cell and/or other immune cell engagers is preferred.
  • Thorough knowledge and practical experience in protein engineering, protein expression, protein-protein interaction techniques, protein structure, and biophysical methods. Experience with Fc engineering is a plus
  • Demonstrated experience in managing research technicians
  • Demonstrated experience with bioinformatics techniques and 3D structure visualization softwares
  • Experience in 3D antibody modelling is a plus

Get in touch Luchele Mendes

Michael Bailey International is acting as an Employment Agency in relation to this vacancy.

Reference: 842220303

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