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Principal Scientist - Antibody Discovery

Posted on Jan 9, 2020 by Michael Bailey Associates - Munich

Lausanne, Vaud, Switzerland
Research
1 Apr 2020
Annual Salary
Contract/Project

Leading Biotech company with astonishing growth plans for 2020
As part of this expansion, we are seeking a high stature Principal Scientist

I am currently recruiting for a Global Biopharmaceutical company based in Lausanne, Switzerland.

My client is constructing a subsidiary research division to innovate next generation of bi/multispecific antibodies, diseases of the immuno-oncology and hematopoietic system. At present they have built a new GMP facility, that will manufacture clinical stage molecules for either further development or to in-license. There's currently several assets in phases I - IIb and you will develop these further, fit for market approval.

We are looking for a Principal Scientist with expertise in Antibody Rational Design.

RESPONSIBILITIES:

  • Lead/participate in the design, characterization and developability of bi/multispecific antibodies
  • Participate in the development of innovative solutions to engineer and characterize antibodies and novel antibody formats
  • Lead/participate in Fc engineering projects
  • Support team to address complex processes and transition leads for industrialization
  • Accomplish goals under project team timelines
  • Interface with multiple discovery project and Matrix teams across the organization
  • Effectively manage projects and resources to maximize progress
  • Effectively communicate research progress and opportunities to senior management
  • Support publications in high-tier journals and present at international meetings
  • Support a culture that embraces scientific excellence, continuous learning, and increasing team's ability to deliver novel drug candidates.

Education and Desired Experience:

  • Ph.D. in Molecular Biology, Biochemistry, Structural Biology or related fields with at least 5 years of relevant industrial experience.
  • Hands-on experience with making T cell and/or other immune cell engagers is preferred.
  • Thorough knowledge and practical experience in protein engineering, protein expression, protein-protein interaction techniques, protein structure, and biophysical methods. Experience with Fc engineering is a plus
  • Demonstrated experience in managing research technicians
  • Demonstrated experience with bioinformatics techniques and 3D structure visualization softwares
  • Experience in 3D antibody modelling is a plus
  • Ability to work with flexibility in a changing and demanding environment
  • Demonstrated success with problem analysis/solving, anticipation and proactivity
  • Strong sense of discipline and initiative, exceptional planning and organization skills and an hands-on approach to work
  • Fluency in English, both written and verbal.

Kontakt: Luchele Mendes

Michael Bailey International is acting as an Employment Agency in relation to this vacancy.

Reference: 824977955

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